1. RNA polymerase holoenzymes containing other sigma factors recognize different core promoter sequences. 2. One exception to this organization is in ? 54-type sigma factors . 3. In bacteria, the sigma factor recognizes and binds to the promoter sequence. 4. Sigma factors are specialized bacterial proteins that bind to RNA polymerases and orchestrate transcription initiation.5. Once initiation of RNA transcription is complete, the sigma factor can leave the complex. 6. Notes : Promoter sequences are specific to the different sigma factors associated to the RNA polymerase core. 7. An example of a core enzyme is a RNA polymerase enzyme without the sigma factor ( ? ). 8. This protein is an anti-sigma factor which has been named " Audrey Stevens'Inhibitor ". 9. RNA polymerase holoenzyme complex consisting of core RNA polymerase and a sigma factor executes transcription of a DNA template strand. 10. This thermosensor upregulates heat shock proteins under high temperatures through ? 32, a specialised heat-shock sigma factor .
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